Misano has hosted world superbike/supersport racing since 1991 and, officially, this is known as the San Marino round, although the circuit itself is on the border of the tiny principality and is technically in Italy. This is always a favourite venue of fans and riders, who flock to the circuit to enjoy the pleasant climate and neighbouring beach.

Technically, the track has a relatively simple layout made up mostly of second and third gear bends. The exception is the long back straight, which is preceded by a fast left hand corner. The circuit is also renowned for inconsistent grip levels. This is partly due to the bumpy surface, which features many different types of tarmac due to work carried out since the circuit opened in 1972 but also due to location and weather conditions. Sea salt can contaminate the track surface to make early morning laps slippery, while the often high temperatures will test the tyres and suspension towards the end of the race.